Priligy alternatives: practical options if dapoxetine isn’t right for you

Priligy (dapoxetine) works fast for many men, but it isn’t the only way to treat premature ejaculation (PE). Maybe you had side effects, cost issues, or your doctor won’t prescribe it. Good news: there are safe alternatives—both drug and non-drug—that can help you last longer and feel more in control.

Medical alternatives

Several prescription drugs are used off-label for PE. They work differently, so talk to your doctor before trying them.

- Short-term SSRIs: Drugs like sertraline, paroxetine, and fluoxetine can delay ejaculation. Unlike dapoxetine, they often need daily dosing and can take days to weeks to work. Watch for common SSRI effects: nausea, sleep changes, or reduced libido.

- Tramadol (off-label): A pain medicine that can delay ejaculation for some men. It carries risks—drowsiness, nausea, and dependence—so only use it under strict medical supervision.

- Clomipramine: A tricyclic antidepressant sometimes prescribed for PE. It can be effective but may have stronger side effects than SSRIs.

- PDE5 inhibitors (sildenafil, tadalafil): These drugs treat erectile dysfunction but can help some men with PE when ED coexists. They aren’t a direct PE fix but worth considering if performance anxiety or erection problems are present. Read our guide on Silvitra and other ED options for more on this topic.

Topical treatments and devices

- Lidocaine/prilocaine creams or sprays: Apply to the head of the penis about 10–20 minutes before sex, then wipe off excess. They numb sensation and can add a few minutes. Use caution to avoid numbing your partner—covering with a condom helps.

- Desensitizing condoms: Thicker condoms or those with a mild numbing agent can reduce sensitivity and delay ejaculation. They also provide STI protection.

Non-prescription supplements are marketed for PE, but evidence is weak. If you try herbal pills, check interactions and buy from reputable sources.

Behavioral and lifestyle options

- Stop-start and squeeze techniques: These simple exercises are done during sex or masturbation to train better control. Many men improve with practice.

- Pelvic floor exercises (Kegels): Strengthening those muscles helps with control. Aim for short, frequent sets—your doctor or physio can show you how.

- Therapy and counseling: Performance anxiety and stress cause or worsen PE. Sex therapy or cognitive behavioral therapy (CBT) helps most guys regain confidence and lasting power.

What to try first? If you want a quick test, topical sprays or condoms are low-risk. For longer-term improvement, combine behavioral work with medical help. Always tell your doctor about other meds and health problems—some options have interaction or safety issues. Want more on related treatments? Check our articles on natural ways to boost male performance and affordable ED options for practical tips.

If you’re unsure which path fits you, ask a clinician who knows sexual medicine. A short conversation can point you to a safe, effective plan that fits your life and goals.